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Academic Calendar 2013 UNDERGRADUATE COURSE INFORMATION Pharmacology (M)
INTRODUCTION
UNDERGRADUATE SESSIONAL DATES
STUDENT SERVICES
ACADEMIC INFORMATION
STUDENT FINANCIAL SERVICES
FACULTIES
UNDERGRADUATE COURSE INFORMATION
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GLOSSARY
NEW MODULES/PROGRAMS
FIRST YEAR UPDATES
TABLE OF CONTENTS




Pharmacology (M)
Pharmacology 2060A/B - Introductory Pharmacology and Therapeutics
A course for students in the BSc in Nursing and other Health Sciences programs as well as students in BMSc and BSc programs, to provide a basic understanding of the fundamentals of drug action and the mechanisms of action and therapeutic use of the important classes of drugs.
Antirequisite(s): Pharmacology 3620, the former Pharmacology 3550A/B.    
Prerequisite(s):
Corequisite(s):
Pre-or Corequisite(s): One of Biology 1001A or 1201A and one of Biology 1002B or 1202B, or the former Biology 1222 or 1223; or registration in the BSc in Nursing.
Extra Information: 1 tutorial hour (optional), 0.5 course. Only offered online (Distance Studies).
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Pharmacology 3580Y - Pharmacology Laboratory
A series of laboratory exercises, tutorials and presentations which introduce students to some of the basic approaches used in Pharmacology.
Antirequisite(s):
Prerequisite(s): Biochemistry 2280A and either Chemistry 2213A/B or 2273A, or permission of the Department. A minimum average of 75% in the previous year is required.
Corequisite(s):
Pre-or Corequisite(s): Pharmacology 3620, or the former Pharmacology 3550A/B and 3560A/B.
Extra Information: 3 laboratory hours (3 laboratory hours every other week and up to 3 tutorial hours, at the instructor's discretion, in alternate weeks). 0.5 course
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Pharmacology 3620 - Human Pharmacology and Therapeutic Principles
A systems-based pharmacology course surveying the range of drugs used to treat disease processes affecting various organs of the body (e.g. cardiovascular disease, neurological diseases, etc.) with emphasis on drug targets, mechanisms of drug action, and adverse effects.
Antirequisite(s): The former Pharmacology 3550A/B, 3560A/B.
Prerequisite(s): Biochemistry 2280A; Biology 2382B.
Corequisite(s):
Pre-or Corequisite(s): Physiology 3120 is strongly recommended.
Extra Information: 2 lecture hours, 1.0 course.
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Pharmacology 4320A/B - Cardiovascular Pharmacology
Basic principles of cardiovascular pharmacology with particular emphasis on cellular mechanisms of drug action and mechanisms of therapeutic efficacy in disease states.
Antirequisite(s):
Prerequisite(s): Pharmacology 3620 (or the former Pharmacology 3550A/B) and Pharmacology 3580Y; or Physiology 3120; or Pharmacology 3620 (or the former Pharmacology 3550A/B) and registration in Year 4 of a module in Pathology and Toxicology; or permission of the Department.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2 lecture hours, 0.5 course.
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Pharmacology 4340A/B - Gene Expression Pathways in Drug Discovery
This course explores how drugs and endogenous compounds mediate their biological effects through nuclear signalling pathways. The emphasis will be on aspects of gene regulation and signalling by nuclear hormone receptors a family of ligand dependent transcription factors essential for normal metabolism, development and reproduction.
Antirequisite(s):
Prerequisite(s): Biochemistry 2280A and registration in Year 4, or permission of the Department.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2 lecture hours, 0.5 course.
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Pharmacology 4350A/B - Clinical Pharmacology
Clinical pharmacology is a scientific and medical discipline dedicated to the bench-to-bedside study of drug action through an in-depth knowledge of human pharmacology and therapeutics. This course in clinical pharmacology focuses on fundamental concepts highlighted with examples from clinical cases, therapeutic applications and relevance to drug discovery and development.
Antirequisite(s):
Prerequisite(s): Pharmacology 3620, or the former Pharmacology 3550A/B and 3560A/B.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2 lecture hours, 0.5 course.
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Pharmacology 4360A/B - Mechanisms of Cancer Chemotherapy
This course is designed to give students a basic understanding of the molecular pharmacology and therapeutic properties of anticancer agents. The focus is on molecular mechanisms of cancer chemotherapy, and will include drug resistance and the roles of receptor kinases and G protein-coupled receptors in existing and novel cancer therapies.
Antirequisite(s):
Prerequisite(s): Pharmacology 3620 or the former Pharmacology 3550A/B and 3560A/B, or Physiology 3140A, or permission of the Department.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2 lecture hours, 0.5 course.
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Pharmacology 4370A/B - The Pharmacology of Drugs of Abuse
This course will cover the pharmacological and pathophysiological effects of non-medicinal drug use including mechanisms of action, tolerance and addiction, long-term effects, side effects and toxicity, treatment of addictions and overdoses. Pharmacokinetics will also be examined including routes of administration, activation, deactivation, elimination, and drug-drug interactions.
Antirequisite(s):
Prerequisite(s): Pharmacology 3620 or Physiology 3140A, or the former Pharmacology 3550A/B and 3560A/B.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2 lecture hours, 0.5 course.
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Pharmacology 4380A/B - Neuropharmacology
This course will focus on the cellular and molecular mechanisms underlying the actions of drugs on the central and peripheral nervous systems. The focus will be on recent developments in the field of neuroscience and their impact on our understanding of the actions, and development of, new drugs.
Antirequisite(s):
Prerequisite(s): Pharmacology 3620, or the former Pharmacology 3550A/B and 3560A/B; Physiology 3140A; or permission of the Department.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2 lecture hours, 0.5 course.
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Pharmacology 4430A/B - Pharmacology and Toxicology of Natural-Sourced Medicines
Contemporary use of medicines derived from natural sources. Regulatory aspects of their use and the scientific basis for assessment of efficacy, quality, and safety of these products will be discussed. The mechanism(s) of beneficial and harmful effects of selected natural health products, including herb-drug interactions, will be included.
Antirequisite(s):
Prerequisite(s): Pharmacology 3620, or the former Pharmacology 3550A/B and 3560A/B; or permission of the Department.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2 lecture hours per week, 1 tutorial hour, 0.5 course.
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Pharmacology 4540A/B - From Genes to Therapies: Targeted Strategies in Medicine
An examination of how mechanisms that regulate cell proliferation affect normal tissue repair and cause abnormalities, such as tumour formation and poor regeneration after injury. The course explores the basic molecular and cellular processes of relevant human disorders and the clinically useful pharmacological and regenerative medical therapies.
Antirequisite(s):
Prerequisite(s): Physiology 3120; Physiology 3140A or Biology 3316A/B; Pharmacology 3620, or the former Pharmacology 3550A/B and 3560A/B; or permission of the Department.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2.0 lecture hours, 0.5 course.
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Pharmacology 4620A - Molecular Mechanisms of Drug Action
This course is focussed on the molecular mechanisms underlying the biological effects of drugs. Content includes: i) advanced drug-receptor theory, ii) theoretical models used to predict drug effects, and iii) chemical structure-activity relationships and modern receptor structure-function analyses as they relate to drug action.
Antirequisite(s):
Prerequisite(s): Pharmacology 3620, or the former Pharmacology 3550A/B and 3560A/B, or Biochemistry 3381A; or permission of the Department.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2 lecture hours, 0.5 course.
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Pharmacology 4630A - Principles of Toxicology
Advanced studies on how chemicals produce undesirable effects in biological systems. Case study and problem-solving approaches will be used to illustrate underlying principles that govern the disposition of toxic chemical agents and dose-response relationship. Biochemical and molecular mechanisms of various forms of chemical toxicities will be examined.
Antirequisite(s):
Prerequisite(s): Pharmacology 3620 (or the former Pharmacology 3560A/B) and Pharmacology 3580Y; or Pharmacology 3620 (or the former Pharmacology 3560A/B) and registration in Year 4 of a module in Pathology and Toxicology; or permission of the Department.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2 lecture hours, 0.5 course.
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Pharmacology 4660A/B - Human Toxicology
A course dealing with the pharmacological and toxicological principles underlying the adverse effects of xenobiotics in humans. In addition to reviewing mechanisms of toxicity in humans, the course will include overviews of the principles of management of human poisoning, the principles of chronic toxicity and of drug safety in humans.
Antirequisite(s):
Prerequisite(s): Pharmacology 3620, or the former Pharmacology 3560A/B, or permission of the Department .
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: 2 lecture hours, 0.5 course
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Pharmacology 4980E - Experimentation and Communication in Pharmacology
Course requirements: i) theory and practice of modern laboratory techniques, laboratory safety, appropriate use of experimental models, ii) independent research project supervised by faculty, iii) scientific communication consisting of instruction on communication skills, preparation of seminar, poster presentation and preparation of a research proposal and final research project written report.
Antirequisite(s):
Prerequisite(s): Pharmacology 3620 (or the former Pharmacology 3550A/B and 3560A/B) and Pharmacology 3580Y; Physiology 3120; Physiology 3140A; and registration in either an Honors Specialization in Pharmacology or an Honors Specialization in Physiology and Pharmacology.
Corequisite(s):
Pre-or Corequisite(s):
Extra Information: Minimum 11 laboratory hours per week plus 2 seminar hours on alternate weeks, 1.5 course.
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Academic Calendar 2013 UNDERGRADUATE COURSE INFORMATION Pharmacology (M)
Decision Academic