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Medical Biophysics (M)
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Medical Biophysics
2582B -
Imaging in Biology
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The course will provide an introduction to concepts that are involved in the imaging and quantification of biological processes using light, radiation and electromagnetism. Students will be introduced to methods used to visualize gene expression, protein synthesis, and molecular processes within cells and organs.
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Biochemistry 2280A; 1.0 course from Applied Mathematics 1201A/B, Calculus 1000A/B, 1301A/B, 1500A/B, 1501A/B, Mathematics 1225A/B, 1228A/B, 1229A/B, 1600A/B, Statistical Sciences 1024A/B; and 1.0 course from Physics 1028A/B, 1029A/B, 1301A/B, 1302A/B, 1501A/B, 1502A/B.
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Biology 2581B.
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Medical Biophysics
3330F/G -
Human Biomechanics with Biomedical Applications
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The mechanical properties of biological structures and fluids in relation to function: deformability, strength, and visco-elasticity of hard and soft tissues, modes of loading and failure. Special topics include mechanics of synovial joints, mechanics of hearing, and mechanics of orthopedic implants and joint replacement.
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Medical Biophysics
3336F/G -
Human & Animal Interactions with the Physical Environment
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Examination of the physical processes in the environment that affect life, and physical processes in animals and man that enable them to survive. Topics include pressure, temperature, light, gravity, sound, ionizing and nonionizing radiation. Special topics: heat exchange, vision and hearing, altitude and diving, the space environment, and radiation tolerance.
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Medical Biophysics
3501A -
Biophysics of Transport Systems
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The physics of blood flow and vascular mechanics in the microcirculation and large vessels, surface energy and interactions at biological interfaces such as the lung, diffusive and convective transport and exchange.
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Medical Biophysics
3503G -
Fundamentals of Digital Imaging
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Concepts of images relevant to all imaging modalities. Image formation and capture including digital cameras and the eye, pixels, aliasing, resolution, contrast, sensitivity, specificity, ROC, window/level, dynamic range, RGB, spectroscopy. Image compression and quality, quantitative analysis based on imaging software and principles of quantitative stereology.
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Medical Biophysics
3505F -
Mathematical Transform Applications in Medical Biophysics
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The role of mathematical tranforms in biomedical research. Application of Fourier Transforms for imaging and image analysis. Applications of systems analysis and Laplace Transforms to model complex systems, and of linear time-invariant systems and kinetic models to analyze physiological processes.
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Medical Biophysics
3507G -
Analysis of Oxygen Transport in Biological Systems
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The application of physics and mathematics for modeling oxygen transport. Emphasis on problem solving and simple MATLAB computer models for enhancing the students’ interpretation of analytical solutions. Topics include the Krogh-Erlang capillary model, microvascular blood flow, oxygen diffusion in thin tissues and tumors, and finite difference models in unsteady-state systems.
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Medical Biophysics
3645A/B -
Introduction to Biomedical Optics
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An introduction to the physical and biophysical principles underlying the methodology and technology for the medical uses of light including diagnostic and therapeutic applications. Specific areas will include: instrumentation which involves light detection and analysis, light spectroscopy which involves photodynamic therapy and diffuse optical tomography and optical imaging.
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Medical Biophysics
3970Z -
General Biophysics Laboratory
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Intended primarily for students in Honors Specialization and Major modules in Medical Biophysics. Laboratories include topics from biomechanics (mechanical properties of arteries and bone), imaging (quantitative stereology, optical CT), biophysical analysis (diffusion and washout models), and transport systems (cardiovascular fluid dynamics). Includes an individual 6-week project in a research laboratory.
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Medical Biophysics
4445A/B -
Digital Imaging Processing
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An introduction to the fundamentals of digital image processing including image representation, 2D linear systems theory and Fourier analysis, digital filtering and segmentation. Concentrates on practical techniques through an exposure to image processing applications in industry, science and medicine and assignments based on MATLAB numeric computation and visualization environments.
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Medical Biophysics
4455A/B -
Biological Control Systems
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An introduction to linear systems and control theory as applied to organ system regulation and adaptation. Emphasis is placed on biophysical models of the respiratory and cardiovascular systems, and interactions with medical devices.
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Medical Biophysics
4467A/B -
Radiation Biology with Biomedical Applications
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Nature and effects of ionizing radiation on biomolecular structures, living cells and tissues. Genetic effects and methods of radiation protection. Radiobiological implications of diagnostic and therapeutic radiation.
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Medical Biophysics
4475A/B -
Medical Imaging
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Physical principles underlying medical imaging. Modalities covered: x-rays, computed tomography, nuclear medicine, ultra-sound, and magnetic resonance imaging. Topics include signal generation, detection and the associated mathematics to produce medically useful images, and factors affecting resolution and sensitivity.
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Medical Biophysics
4535A/B -
Hemodynamics
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Biophysics related to blood flow: Biomechanical properties of blood, heart, arteries, and veins; pressure, flow, and Poiseulle's law; optimality principles; fluid flow conservation laws and their mathematical description; pulsatile flow in rigid vessels; wave propagation in elastic vessels; structure and blood rheology of the microcirculation; oxygen delivery and flow regulation.
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Medical Biophysics
4518B -
Molecular Imaging
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An introduction to the role of diagnostic imaging in detecting molecules, genes, and cells in vivo. The emphasis is on how these techniques assist in studying molecular mechanisms of disease in vivo. Topics include DNA/protein synthesis, transgenic mice, novel contrast agents and small animal imaging.
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Medical Biophysics
4600A/B -
Special Topics in Medical Biophysics
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Selected topics of current interest in Medical Biophysics.
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Permission of the Department of Medical Biophysics.
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Medical Biophysics
4970E -
Research Project in Biophysics
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Major laboratory course in experimental biophysics for Honors Specialization modules offered by the Department of Medical Biophysics. Three components are: a major experimental project (topic and advisor chosen in consultation with the student), scientific communication (student presentation and reports), and electronic information processing (data capture, computer analysis of biophysical signals).
Prerequisite(s):
Medical Biophysics 3970Z and registration in Year 4 of one of the following Honors Specialization modules: Medical Biophysics (Medical Science Concentration), Medical Biophysics (Physical Science Concentration), or Medical Biophysics (Biological Science Concentration); or registration in Year 4 of an Honors Specialization in Medical Biophysics and Biochemistry plus either Medical Biophysics 3970Z or Biochemistry 3380G.
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Medical Biophysics
4971E -
Research Project in Biophysics (Clinical Physics Concentration)
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Major laboratory course in experimental biophysics for fourth-year Honors Specialization Medical Biophysics (Clinical Physics Concentration). The three components are: a major experimental project related to Clinical Physics (topic and advisor chosen in consultation with the student), scientific communication (student presentation and reports), and electronic information processing (data capture, computer analysis of biophysical signals).
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Medical Biophysics 3970Z and registration in Year 4 of an Honors Specialization in Medical Biophysics (Clinical Physics Concentration).
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