Mutation of specific human genes subverts normal cellular physiology creating characteristic alterations called ‘hallmarks’ that fuel the development of cancer. The underlying processes that alter cellular pathways and gene function will be discussed. Cancer models and molecular therapies will be related to the cancer hallmarks.

Antirequisite(s): Biochemistry 4450A.

Prerequisite(s): Biology 2581A/B; and either Pathology 3500 or Biochemistry 3381A.

Extra Information: 2 lecture hours. Cross-listed with Biochemistry 4450A.