Academic Calendar - 2018 ARCHIVE
Western University Academic Calendar. - 2018ARCHIVE
Medical Biophysics
The course will provide an introduction to concepts that are involved in the imaging and quantification of biological processes using light, radiation and electromagnetism. Students will be introduced to methods used to visualize gene expression, protein synthesis, and molecular processes within cells and organs.
Prerequisite(s): Biochemistry 2280A; 1.0 course from Applied Mathematics 1201A/B, Calculus 1000A/B, Calculus 1301A/B, Calculus 1500A/B, Calculus 1501A/B, Mathematics 1225A/B, Mathematics 1228A/B, Mathematics 1229A/B, Mathematics 1600A/B, Statistical Sciences 1024A/B; and 1.0 course from Physics 1028A/B, Physics 1029A/B, Physics 1301A/B, Physics 1302A/B, Physics 1501A/B, Physics 1502A/B.
Pre-or Corequisite(s): Biology 2581A/B.
Extra Information: 3 lecture hours.
Course Weight: 0.50
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The mechanical properties of biological structures and fluids in relation to function: deformability, strength, and visco-elasticity of hard and soft tissues, modes of loading and failure. Special topics include mechanics of synovial joints, mechanics of hearing, and mechanics of orthopedic implants and joint replacement.
Prerequisite(s): One of Calculus 1000A/B, Calculus 1500A/B, Mathematics 1225A/B, Applied Mathematics 1413; one of Physics 1028A/B, Physics 1301A/B, Physics 1401A/B or Physics 1501A/B, and one of Physics 1029A/B, Physics 1302A/B, Physics 1402A/B or Physics 1502A/B. Typically taken in third year, this course is also open to second-year students with an overall average of at least 70% in first year.
Extra Information: 3 lecture hours, 2 laboratory/tutorial hours.
Course Weight: 0.50
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Examination of the physical processes in the environment that affect life, and physical processes in animals and man that enable them to survive. Topics include pressure, temperature, light, gravity, sound, ionizing and nonionizing radiation. Special topics: heat exchange, vision and hearing, altitude and diving, the space environment, and radiation tolerance.
Prerequisite(s): One of Biology 1001A or Biology 1201A and one of Biology 1002B or Biology 1202B; one of Physics 1028A/B, Physics 1301A/B, Physics 1401A/B or Physics 1501A/B, and one of Physics 1029A/B, Physics 1302A/B, Physics 1402A/B or Physics 1502A/B. Typically taken in third year, this course is also open to second-year students with an overall average of at least 70% in first year.
Pre-or Corequisite(s): Calculus 1000A/B, Calculus 1500A/B plus one of Calculus 1301A/B or Calculus 1501A/B, or Applied Mathematics 1413.
Extra Information: Typically taken in third year, this course is also open to second-year students with an overall average of at least 70% in first year. 2 lecture hours, 1 tutorial hour.
Course Weight: 0.50
Return to top
The physics of blood flow and vascular mechanics in the microcirculation and large vessels, surface energy and interactions at biological interfaces such as the lung, diffusive and convective transport and exchange.
Prerequisite(s): One of Calculus 1000A/B, Calculus 1500A/B, Mathematics 1225A/B, Applied Mathematics 1413; one of Physics 1028A/B, Physics 1301A/B, Physics 1401A/B or Physics 1501A/B, and one of Physics 1029A/B, Physics 1302A/B, Physics 1402A/B or Physics 1502A/B.Typically taken in third year, this course is also open to second-year students with an overall average of at least 70% in first year.
Extra Information: 2 lecture hours, 1 tutorial hour.
Course Weight: 0.50
Return to top
Concepts of images relevant to all imaging modalities. Image formation and capture including digital cameras and the eye, pixels, aliasing, resolution, contrast, sensitivity, specificity, ROC, window/level, dynamic range, RGB, spectroscopy. Image compression and quality, quantitative analysis based on imaging software and principles of quantitative stereology.
Prerequisite(s): Calculus 1000A/B or Calculus 1500A/B plus one of Calculus 1301A/B or Calculus 1501A/B, or Applied Mathematics 1413; one of Physics 1028A/B, Physics 1301A/B, Physics 1401A/B or Physics 1501A/B, and one of Physics 1029A/B, Physics 1302A/B, Physics 1402A/B or Physics 1502A/B. Typically taken in third year, this course is also open to second-year students with an average of at least 70% in first year.
Extra Information: 2 lecture hours, 1 tutorial hour.
Course Weight: 0.50
Return to top
The role of mathematical transforms in biomedical research. Application of Fourier Transforms for imaging and image analysis. Applications of systems analysis and Laplace Transforms to model complex systems, and of linear time-invariant systems and kinetic models to analyze physiological processes.
Prerequisite(s): One of Calculus 1000A/B, Calculus 1500A/B plus one of Calculus 1301A/B or Calculus 1501A/B, or Applied Mathematics 1413; one of Physics 1028A/B, Physics 1301A/B, Physics 1401A/B or Physics 1501A/B, and one of Physics 1029A/B, Physics 1302A/B, Physics 1402A/B or Physics 1502A/B. Although typically taken in third year, this course is available to second-year students with an overall average of at least 70% in first year.
Extra Information: 2 lecture hours, 2 laboratory/tutorial hours.
Course Weight: 0.50
Return to top
The application of physics and mathematics for modeling oxygen transport. Emphasis on problem solving and simple MATLAB computer models for enhancing the students' interpretation of analytical solutions. Topics include the Krogh-Erlang capillary model, microvascular blood flow, oxygen diffusion in thin tissues and tumors, and finite difference models in unsteady-state systems.
Prerequisite(s): One of Calculus 1000A/B, Calculus 1500A/B plus one of Calculus 1301A/B or Calculus 1501A/B, or Applied Mathematics 1413; one of Physics 1028A/B, Physics 1301A/B, Physics 1401A/B or Physics 1501A/B, and one of Physics 1029A/B, Physics 1302A/B, Physics 1402A/B or Physics 1502A/B. Although typically taken in third year, this course is available to second-year students with an overall average of at least 70% in first year.
Extra Information: 2 lecture hours, 2 laboratory/tutorial hours.
Course Weight: 0.50
Return to top
An introduction to the physical and biophysical principles underlying the methodology and technology for the medical uses of light including diagnostic and therapeutic applications. Specific areas will include: instrumentation which involves light detection and analysis, light spectroscopy which involves photodynamic therapy and diffuse optical tomography and optical imaging.
Prerequisite(s): One of Calculus 1000A/B or Calculus 1500A/B plus one of Calculus 1301A/B or Calculus 1501A/B, or Applied Mathematics 1413; one of Physics 1028A/B, Physics 1301A/B, Physics 1401A/B or Physics 1501A/B, plus one of Physics 1029A/B, Physics 1302A/B, Physics 1402A/B or Physics 1502A/B.
Extra Information: 2 lecture hours.
Course Weight: 0.50
Return to top
Intended primarily for students in Honors Specialization and Major modules in Medical Biophysics. Laboratories include topics from biomechanics (mechanical properties of arteries and bone), imaging (quantitative stereology, optical CT), biophysical analysis (diffusion and washout models), and transport systems (cardiovascular fluid dynamics). Includes an individual 6-week project in a research laboratory.
Pre-or Corequisite(s): Medical Biophysics 3330F/G, Medical Biophysics 3501A and Medical Biophysics 3505F; or Medical Biophysics 3501A and Medical Biophysics 3507G and registration in the Honors Specialization in Medical Biophysics and Biochemistry.
Extra Information: 3 laboratory hours (3 laboratory hours every other week and up to 3 tutorial hours, at the instructor's discretion, in alternate weeks).
Course Weight: 0.50
Return to top
An introduction to the fundamentals of digital image processing including image representation, 2D linear systems theory and Fourier analysis, digital filtering and segmentation. Concentrates on practical techniques through an exposure to image processing applications in industry, science and medicine and assignments based on MATLAB numeric computation and visualization environments.
Prerequisite(s): Medical Biophysics 3503G, 3505F and 3507G; Calculus 2303A/B or 2503A/B; Physics 2101A/B and 2102A/B; or permission of the department.
Extra Information: 3 lecture hours.
Course Weight: 0.50
Return to top
An introduction to linear systems and control theory as applied to organ system regulation and adaptation. Emphasis is placed on biophysical models of the respiratory and cardiovascular systems, and interactions with medical devices.
Prerequisite(s): Medical Biophysics 3501A and Medical Biophysics 3505F; or permission of the department.
Extra Information: 3 lecture hours.
Course Weight: 0.50
Return to top
Nature and effects of ionizing radiation on biomolecular structures, living cells and tissues. Genetic effects and methods of radiation protection. Radiobiological implications of diagnostic and therapeutic radiation.
Prerequisite(s): Medical Biophysics 3501A; one of Medical Biophysics 3507G or Physics 2101A/B or Physics 2102A/B; or permission of the department.
Extra Information: 2 lecture hours.
Course Weight: 0.50
Return to top
Physical principles underlying medical imaging. Modalities covered: x-rays, computed tomography, nuclear medicine, ultra-sound, and magnetic resonance imaging. Topics include signal generation, detection and the associated mathematics to produce medically useful images, and factors affecting resolution and sensitivity.
Prerequisite(s): Medical Biophysics 3503G, Medical Biophysics 3505F and Medical Biophysics 3507G; Physics 2101A/B and Physics 2102A/B, or permission of the department.
Extra Information: 3 lecture hours.
Course Weight: 0.50
Return to top
An introduction to the role of diagnostic imaging in detecting molecules, genes, and cells in vivo. The emphasis is on how these techniques assist in studying molecular mechanisms of disease in vivo. Topics include DNA/protein synthesis, transgenic mice, novel contrast agents and small animal imaging.
Prerequisite(s): Biochemistry 2280A; Medical Biophysics 3501A.
Extra Information: 2 lecture hours.
Course Weight: 0.50
Return to top
Biophysics related to blood flow: Biomechanical properties of blood, heart, arteries, and veins; pressure, flow, and Poiseulle's law; optimality principles; fluid flow conservation laws and their mathematical description; pulsatile flow in rigid vessels; wave propagation in elastic vessels; structure and blood rheology of the microcirculation; oxygen delivery and flow regulation.
Prerequisite(s): Medical Biophysics 3501A, Medical Biophysics 3503G, Medical Biophysics 3505F and Medical Biophysics 3507G; or permission of the department.
Extra Information: 2 lecture hours.
Course Weight: 0.50
Return to top
Selected topics of current interest in Medical Biophysics.
Prerequisite(s): Permission of the Department.
Extra Information: 3 lecture hours.
Course Weight: 0.50
Return to top
Major laboratory course in experimental biophysics for Honors Specialization modules offered by the Department of Medical Biophysics. Three components are: a major experimental project (topic and advisor chosen in consultation with the student), scientific communication (student presentation and reports), and electronic information processing (data capture, computer analysis of biophysical signals).
Antirequisite(s): Medical Biophysics 4971E.
Prerequisite(s): Medical Biophysics 3970Z and registration in Year 4 of one of the following Honors Specialization modules: Medical Biophysics (Medical Science Concentration), Medical Biophysics (Physical Science Concentration), or Medical Biophysics (Biological Science Concentration); or registration in Year 4 of an Honors Specialization in Medical Biophysics and Biochemistry plus either Medical Biophysics 3970Z or Biochemistry 3380G.
Extra Information: 15 hours weekly on average.
Course Weight: 1.50
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Major laboratory course in experimental biophysics for fourth-year Honors Specialization Medical Biophysics (Clinical Physics Concentration). The three components are: a major experimental project related to Clinical Physics (topic and advisor chosen in consultation with the student), scientific communication (student presentation and reports), and electronic information processing (data capture, computer analysis of biophysical signals).
Antirequisite(s): Medical Biophysics 4970E.
Prerequisite(s): Medical Biophysics 3970Z and registration in Year 4 of an Honors Specialization in Medical Biophysics (Clinical Physics Concentration).
Extra Information: 15 hours weekly on average.
Course Weight: 1.50
Return to top
Medical Biophysics
The course will provide an introduction to concepts that are involved in the imaging and quantification of biological processes using light, radiation and electromagnetism. Students will be introduced to methods used to visualize gene expression, protein synthesis, and molecular processes within cells and organs.
Prerequisite(s): Biochemistry 2280A; 1.0 course from Applied Mathematics 1201A/B, Calculus 1000A/B, Calculus 1301A/B, Calculus 1500A/B, Calculus 1501A/B, Mathematics 1225A/B, Mathematics 1228A/B, Mathematics 1229A/B, Mathematics 1600A/B, Statistical Sciences 1024A/B; and 1.0 course from Physics 1028A/B, Physics 1029A/B, Physics 1301A/B, Physics 1302A/B, Physics 1501A/B, Physics 1502A/B.
Pre-or Corequisite(s): Biology 2581A/B.
Extra Information: 3 lecture hours.
Course Weight: 0.50
Return to top
The mechanical properties of biological structures and fluids in relation to function: deformability, strength, and visco-elasticity of hard and soft tissues, modes of loading and failure. Special topics include mechanics of synovial joints, mechanics of hearing, and mechanics of orthopedic implants and joint replacement.
Prerequisite(s): One of Calculus 1000A/B, Calculus 1500A/B, Mathematics 1225A/B, Applied Mathematics 1413; one of Physics 1028A/B, Physics 1301A/B, Physics 1401A/B or Physics 1501A/B, and one of Physics 1029A/B, Physics 1302A/B, Physics 1402A/B or Physics 1502A/B. Typically taken in third year, this course is also open to second-year students with an overall average of at least 70% in first year.
Extra Information: 3 lecture hours, 2 laboratory/tutorial hours.
Course Weight: 0.50
Return to top
Examination of the physical processes in the environment that affect life, and physical processes in animals and man that enable them to survive. Topics include pressure, temperature, light, gravity, sound, ionizing and nonionizing radiation. Special topics: heat exchange, vision and hearing, altitude and diving, the space environment, and radiation tolerance.
Prerequisite(s): One of Biology 1001A or Biology 1201A and one of Biology 1002B or Biology 1202B; one of Physics 1028A/B, Physics 1301A/B, Physics 1401A/B or Physics 1501A/B, and one of Physics 1029A/B, Physics 1302A/B, Physics 1402A/B or Physics 1502A/B. Typically taken in third year, this course is also open to second-year students with an overall average of at least 70% in first year.
Pre-or Corequisite(s): Calculus 1000A/B, Calculus 1500A/B plus one of Calculus 1301A/B or Calculus 1501A/B, or Applied Mathematics 1413.
Extra Information: Typically taken in third year, this course is also open to second-year students with an overall average of at least 70% in first year. 2 lecture hours, 1 tutorial hour.
Course Weight: 0.50
Return to top
The physics of blood flow and vascular mechanics in the microcirculation and large vessels, surface energy and interactions at biological interfaces such as the lung, diffusive and convective transport and exchange.
Prerequisite(s): One of Calculus 1000A/B, Calculus 1500A/B, Mathematics 1225A/B, Applied Mathematics 1413; one of Physics 1028A/B, Physics 1301A/B, Physics 1401A/B or Physics 1501A/B, and one of Physics 1029A/B, Physics 1302A/B, Physics 1402A/B or Physics 1502A/B.Typically taken in third year, this course is also open to second-year students with an overall average of at least 70% in first year.
Extra Information: 2 lecture hours, 1 tutorial hour.
Course Weight: 0.50
Return to top
Concepts of images relevant to all imaging modalities. Image formation and capture including digital cameras and the eye, pixels, aliasing, resolution, contrast, sensitivity, specificity, ROC, window/level, dynamic range, RGB, spectroscopy. Image compression and quality, quantitative analysis based on imaging software and principles of quantitative stereology.
Prerequisite(s): Calculus 1000A/B or Calculus 1500A/B plus one of Calculus 1301A/B or Calculus 1501A/B, or Applied Mathematics 1413; one of Physics 1028A/B, Physics 1301A/B, Physics 1401A/B or Physics 1501A/B, and one of Physics 1029A/B, Physics 1302A/B, Physics 1402A/B or Physics 1502A/B. Typically taken in third year, this course is also open to second-year students with an average of at least 70% in first year.
Extra Information: 2 lecture hours, 1 tutorial hour.
Course Weight: 0.50
Return to top
The role of mathematical transforms in biomedical research. Application of Fourier Transforms for imaging and image analysis. Applications of systems analysis and Laplace Transforms to model complex systems, and of linear time-invariant systems and kinetic models to analyze physiological processes.
Prerequisite(s): One of Calculus 1000A/B, Calculus 1500A/B plus one of Calculus 1301A/B or Calculus 1501A/B, or Applied Mathematics 1413; one of Physics 1028A/B, Physics 1301A/B, Physics 1401A/B or Physics 1501A/B, and one of Physics 1029A/B, Physics 1302A/B, Physics 1402A/B or Physics 1502A/B. Although typically taken in third year, this course is available to second-year students with an overall average of at least 70% in first year.
Extra Information: 2 lecture hours, 2 laboratory/tutorial hours.
Course Weight: 0.50
Return to top
The application of physics and mathematics for modeling oxygen transport. Emphasis on problem solving and simple MATLAB computer models for enhancing the students' interpretation of analytical solutions. Topics include the Krogh-Erlang capillary model, microvascular blood flow, oxygen diffusion in thin tissues and tumors, and finite difference models in unsteady-state systems.
Prerequisite(s): One of Calculus 1000A/B, Calculus 1500A/B plus one of Calculus 1301A/B or Calculus 1501A/B, or Applied Mathematics 1413; one of Physics 1028A/B, Physics 1301A/B, Physics 1401A/B or Physics 1501A/B, and one of Physics 1029A/B, Physics 1302A/B, Physics 1402A/B or Physics 1502A/B. Although typically taken in third year, this course is available to second-year students with an overall average of at least 70% in first year.
Extra Information: 2 lecture hours, 2 laboratory/tutorial hours.
Course Weight: 0.50
Return to top
An introduction to the physical and biophysical principles underlying the methodology and technology for the medical uses of light including diagnostic and therapeutic applications. Specific areas will include: instrumentation which involves light detection and analysis, light spectroscopy which involves photodynamic therapy and diffuse optical tomography and optical imaging.
Prerequisite(s): One of Calculus 1000A/B or Calculus 1500A/B plus one of Calculus 1301A/B or Calculus 1501A/B, or Applied Mathematics 1413; one of Physics 1028A/B, Physics 1301A/B, Physics 1401A/B or Physics 1501A/B, plus one of Physics 1029A/B, Physics 1302A/B, Physics 1402A/B or Physics 1502A/B.
Extra Information: 2 lecture hours.
Course Weight: 0.50
Return to top
Intended primarily for students in Honors Specialization and Major modules in Medical Biophysics. Laboratories include topics from biomechanics (mechanical properties of arteries and bone), imaging (quantitative stereology, optical CT), biophysical analysis (diffusion and washout models), and transport systems (cardiovascular fluid dynamics). Includes an individual 6-week project in a research laboratory.
Pre-or Corequisite(s): Medical Biophysics 3330F/G, Medical Biophysics 3501A and Medical Biophysics 3505F; or Medical Biophysics 3501A and Medical Biophysics 3507G and registration in the Honors Specialization in Medical Biophysics and Biochemistry.
Extra Information: 3 laboratory hours (3 laboratory hours every other week and up to 3 tutorial hours, at the instructor's discretion, in alternate weeks).
Course Weight: 0.50
Return to top
An introduction to the fundamentals of digital image processing including image representation, 2D linear systems theory and Fourier analysis, digital filtering and segmentation. Concentrates on practical techniques through an exposure to image processing applications in industry, science and medicine and assignments based on MATLAB numeric computation and visualization environments.
Prerequisite(s): Medical Biophysics 3503G, 3505F and 3507G; Calculus 2303A/B or 2503A/B; Physics 2101A/B and 2102A/B; or permission of the department.
Extra Information: 3 lecture hours.
Course Weight: 0.50
Return to top
An introduction to linear systems and control theory as applied to organ system regulation and adaptation. Emphasis is placed on biophysical models of the respiratory and cardiovascular systems, and interactions with medical devices.
Prerequisite(s): Medical Biophysics 3501A and Medical Biophysics 3505F; or permission of the department.
Extra Information: 3 lecture hours.
Course Weight: 0.50
Return to top
Nature and effects of ionizing radiation on biomolecular structures, living cells and tissues. Genetic effects and methods of radiation protection. Radiobiological implications of diagnostic and therapeutic radiation.
Prerequisite(s): Medical Biophysics 3501A; one of Medical Biophysics 3507G or Physics 2101A/B or Physics 2102A/B; or permission of the department.
Extra Information: 2 lecture hours.
Course Weight: 0.50
Return to top
Physical principles underlying medical imaging. Modalities covered: x-rays, computed tomography, nuclear medicine, ultra-sound, and magnetic resonance imaging. Topics include signal generation, detection and the associated mathematics to produce medically useful images, and factors affecting resolution and sensitivity.
Prerequisite(s): Medical Biophysics 3503G, Medical Biophysics 3505F and Medical Biophysics 3507G; Physics 2101A/B and Physics 2102A/B, or permission of the department.
Extra Information: 3 lecture hours.
Course Weight: 0.50
Return to top
An introduction to the role of diagnostic imaging in detecting molecules, genes, and cells in vivo. The emphasis is on how these techniques assist in studying molecular mechanisms of disease in vivo. Topics include DNA/protein synthesis, transgenic mice, novel contrast agents and small animal imaging.
Prerequisite(s): Biochemistry 2280A; Medical Biophysics 3501A.
Extra Information: 2 lecture hours.
Course Weight: 0.50
Return to top
Biophysics related to blood flow: Biomechanical properties of blood, heart, arteries, and veins; pressure, flow, and Poiseulle's law; optimality principles; fluid flow conservation laws and their mathematical description; pulsatile flow in rigid vessels; wave propagation in elastic vessels; structure and blood rheology of the microcirculation; oxygen delivery and flow regulation.
Prerequisite(s): Medical Biophysics 3501A, Medical Biophysics 3503G, Medical Biophysics 3505F and Medical Biophysics 3507G; or permission of the department.
Extra Information: 2 lecture hours.
Course Weight: 0.50
Return to top
Selected topics of current interest in Medical Biophysics.
Prerequisite(s): Permission of the Department.
Extra Information: 3 lecture hours.
Course Weight: 0.50
Return to top
Major laboratory course in experimental biophysics for Honors Specialization modules offered by the Department of Medical Biophysics. Three components are: a major experimental project (topic and advisor chosen in consultation with the student), scientific communication (student presentation and reports), and electronic information processing (data capture, computer analysis of biophysical signals).
Antirequisite(s): Medical Biophysics 4971E.
Prerequisite(s): Medical Biophysics 3970Z and registration in Year 4 of one of the following Honors Specialization modules: Medical Biophysics (Medical Science Concentration), Medical Biophysics (Physical Science Concentration), or Medical Biophysics (Biological Science Concentration); or registration in Year 4 of an Honors Specialization in Medical Biophysics and Biochemistry plus either Medical Biophysics 3970Z or Biochemistry 3380G.
Extra Information: 15 hours weekly on average.
Course Weight: 1.50
Return to top
Major laboratory course in experimental biophysics for fourth-year Honors Specialization Medical Biophysics (Clinical Physics Concentration). The three components are: a major experimental project related to Clinical Physics (topic and advisor chosen in consultation with the student), scientific communication (student presentation and reports), and electronic information processing (data capture, computer analysis of biophysical signals).
Antirequisite(s): Medical Biophysics 4970E.
Prerequisite(s): Medical Biophysics 3970Z and registration in Year 4 of an Honors Specialization in Medical Biophysics (Clinical Physics Concentration).
Extra Information: 15 hours weekly on average.