Physiology 1020 - Human Physiology

A survey course outlining the principles of human/mammalian physiology; general properties of the living cell and the internal environment; neural, muscle, cardiovascular, respiratory, gastrointestinal, renal and endocrine systems; metabolism, reproduction and homeostasis.
2 lecture hours, 1 tutorial hour, 1.0 course.

Physiology 1021 - Introduction to Human Physiology

An introductory course, outlining the principles of human/mammalian physiology along with a general survey of various physiological systems (e.g. cardiovascular, renal, neural, motor, gastrointestinal, endocrine, respiratory, etc.).
2 lecture hours, 1 tutorial hour, 1.0 course.

Physiology 2130 - Human Physiology

A survey course outlining the principles of human/mammalian physiology: general properties of the living cell and internal environment; neural, muscle, cardiovascular, respiratory, gastro-intestinal, renal and endocrine system; metabolism, reproduction, and homeostasis.

Physiology 3120 - Human Physiology

A survey of the physiology of various systems (e.g. neural, endocrine, renal, cardiovascular, digestive, respiratory, etc.) of the human.

Physiology 3140A - Cellular Physiology

 A survey of principles of cellular physiology including membrane, ion channel, receptor, and transport protein function, and signal transduction mechanisms.

Physiology 4100A/B - Digestion and Related Metabolism

This course will cover gastrointestinal secretion, motility, digestion, absorption, hepatic and pancreatic physiology.  Specific areas will include: gut-brain-liver axis and nutrient metabolism, exocrine and endocrine pancreas, liver and lipid metabolism. Relevant pathologies and disease states, including obesity, diabetes, and metabolic syndrome along with current therapeutic strategies will be covered.
Cross-listed with Pharmacology 4100A/B.

Physiology 4200A/B - Current Topics in Respiratory Health and Disease

This course examines the normal pulmonary environment, including lung development and adaptations  to high altitude and exercise, and a variety of pathophysiological conditions and processes. For each condition or disease, physiological abnormalities and current therapies will be discussed, as will pathophysiological mechanisms with some emphasis on chronic and acute inflammation.

Physiology 4420A/B - Physiology of Exercise

A study of the integration of neural, metabolic and vascular factors that compete to simultaneously regulate blood pressure and blood flow during physical exercise in health and disease.
Priority to students in Honors Specialization modules in Physiology, and Physiology and Pharmacology.

Physiology 4510A/B - Understanding Pluripotency: The Physiology of Stem Cell Fate and Function

This course examines the basic molecular, biochemical and morphological events that regulate pluripotent stem cell biology. Students will learn about the physiology, research principles and ethical issues that surround the generation and clinical use of pluripotent stem cells.

Physiology 4520A/B - Stem Cells and Regenerative Medicine

Central concepts in regenerative medicine are explored, with a focus on the pre-clinical development of stem cell therapies. Emphasized are: fundamentals of tissue-specific (post-natal) stem cell isolation, expansion and functional characterization using xenotransplantation into immunodeficient mouse models for the treatment of human hematopoietic disorders, ischemic vascular diseases, diabetes and cancer.

Physiology 4530A/B - Biological Bases of Skeletal Health and Disease

This course will provide an overview of the development and biology of skeletal tissues, introduce current techniques used to study skeletal physiology and examine the biological bases of common musculoskeletal diseases and their treatments.

Physiology 4600A/B - Diseases of Ion Channels

Diseases related to ion channels, including epilepsy, congenital hearing loss, immunodeficiency and cardiac arrhythmias. The physiology and pathophysiology of relevant ion channels will be covered.

Physiology 4610A/B - Cardiovascular Physiology

A study of the regulation of the circulation including factors involved in the regulation of cardiac output, reflex control of the circulation and long-term control of arterial pressure.

Physiology 4620A/B - Reproductive Endocrinology

Selected topics in reproduction and its endocrine regulation.

Physiology 4630A/B - Motor Neurophysiology

A study of the neural control of movement in mammals. Topics include normal and abnormal function of muscle receptors, spinal reflexes, cerebellum, basal ganglia and motor areas of cerebral cortex.

Physiology 4640A/B - Organogenesis in Mammals

Mechanisms underlying the development of selected organs and organ systems in mammals: brain and peripheral nervous system, heart and vascular system, lungs, kidneys, gonads and associated reproductive structures, gastrointestinal tract, and limbs. Emphasis is on the biochemical and morphological maturation pathway that equips each system for its physiological role.

Physiology 4650A/B - Neurophysiology of Homeostasis and Stress

The hypothalamus and limbic system contribute to the neural integration of autonomic, endocrine and skeletomotor responses which contribute to homeostasis and adaptive behaviors. Topics include the regulation of neuroendocrine function, blood pressure, energy and water balance, circadian rhythms and the integration of reproductive function.

Physiology 4660A/B - Body Water and Renal Physiology

Body fluid compartments and kidney function.

Physiology 4670A/B - Selected Advanced Topics in Physiology

A seminar course, by arrangement with the Department of Physiology.

Physiology 4680A/B - Cellular/Molecular Neurobiology

Cellular function and communication in the central nervous system. Topics will cover physiological mechanisms of intrinsic neuronal activity, excitatory and inhibitory synaptic transmission, integrative neuronal activities and protein processing pathways related to neuronal signalling and degeneration in Alzheimer's disease. Specific examples relevant to neuronal functions and dysregulations will be used.

Physiology 4700A/B - Fetal Physiology

This course covers placental function (endocrine, nutrient transport and parturition), fetal growth and development (heart, brain, kidneys, vessels, adipose, liver, lung, muscle and pancreas) and deals with the concept of the fetus as a patient to be followed during poor in utero conditions, such as hypoxia or poor diet.

Physiology 4710A/B - Physiology of the Senses

This course covers the physiology of the senses in the primate, including touch, taste, pain, smell, vision, motion and hearing. Each sensory modality is used to exemplify a particular aspect of sensory processing from stimulus encoding at the periphery to the feature extraction in the sensory cerebral cortex.

Physiology 4730B - Cell Signalling in Tissue, Injury and Repair

Examines the basic principles and surveys molecular mechanisms of regulation of cell growth, adhesion, migration, and differentiation and their functional integration to support survival and development. Dysregulation of these processes in disease will also be examined. The course is composed of both lectures and student presentations of scientific literature.